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He said the biggest challenge was to devise ways of making banks and other participants stick to the new code, which will not have the status of binding regulation, adding that it would be for governments to devise sanctions in the event of market abuse.
ARF proteins are capable, irrespective of auxin status, of binding to auxin responsive cis-elements (AuxRE; TGTCTC) present upstream to the coding sequence of auxin responsive genes [ 4, 5].
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Finally, using methylation dependent immunoprecipitation (MeDIP), we also determine the overall methylation status of MYCN binding sites and observed a striking correlation between MYCN binding and DNA hypermethylation status in the neuroblastoma cell lines studied.
During our analysis of the methylation status of Kaiso binding sites, we noted that there are many more Kaiso binding sites in K562 cells than in GM12878 cells.
These debates about the status of the binding problem (reviewed by Plate, 2007) turn on foundational issues for the cognitive sciences generally.
These cellular mechanisms are orchestrated by transcriptional regulators; therefore changes in the methylation status of their binding sites may disrupt those processes thus contributing to oncogenesis.
The status of polyamide binding at the target promoter region (Table S3) was detected using a ChIP assay kit (Upstate Biotechnology, Upstate Biotechnology, Inc., Lake Placid, NY, USA) following the manufacturer's protocol.
However, in general the occupational profiles still have the status of non-binding recommendations.
Four scores are defined to quantify the functional status of TF target bindings.
To evaluate the changes in NF-κB expression after development of acquired platinum-resistance, we investigated the status of DNA-binding activity of p65 in T24 and T24PR cells using EMSA.
Notably, several studies have documented that the binding ability of transcription factors may be affected by DNA methylation status in their target sites., Accordingly, we analyzed the methylation status of PPARγ-binding sites.
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