In contrast, mutants, 7K and P11, exhibit an IT stat significantly different from wild-type parasites both under tachyzoite conditions (0 h) and bradyzoite conditions (72 h), i.e., the mean expression level of IT genes is ∼9 at both 0 h and 72 h (Figure 7A).
As a result, the predictive power of STAT-Scanner was significantly enhanced by integrating STAT-related PWMs.
With high stats, missions get significantly easier; with low stats, they can become next to impossible.
If you leave a character doing nothing at night, their stats will have significantly dropped in the morning.
The number of stat lab tests significantly decreased after POE.
Cell-cycle and JAK-STAT pathways are significantly altered in lung cancer, along with perturbations in 54 genes that are potentially targetable with currently available drugs.
In comparison to control mice (day 0), expression of STAT-1 was significantly elevated at day 1 of arthritis.
Both TLR, which is an essential upstream regulator of NFκB, and the JAK-STAT pathway were significantly activated only in kras V12 HCC.
We showed that small molecule blockers, CAPE and ruxolitinib, for NF-κB and JAK-STAT pathways, respectively, significantly inhibited cytokine secretion by macrophages.
Compared to Kras G12D adenocarcinomas and Kras G12DLkb1 fl/fl squamous tumors, the Jak-Stat pathway was significantly activated in Sox2-Lkb1 tumors (indicated by phospho-Stat3) with clear nuclear pStat3 in some cells within the squamous tumors.
