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The package adopts the linear modeling approach implemented by lmFit and the empirical Bayesian statistics implemented by eBayes.
To understand population differentiation within T. cacao and to overcome the problem of mislabeled samples, we conducted a study using Bayesian statistics implemented through the software Structure [12].
Admixture proportions were estimated with mY statistics implemented in Admix 2.0.
The phylogenetic tree for the dataset was estimated using Bayesian statistics implemented in MrBayes 3.1.2 [ 35].
All output measurements are analyzed using MATLAB and statistics implemented using custom R scripts.
The spatial scan statistics implemented in SaTScan software [ 45] were used to carry out a cluster analysis to determine the spatial aggregation of infant mortality.
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Usable statistics (see Table 2 for list of currently available statistics) implement the MafStatistics interface.
For the remaining 18793 genes, raw p-values were calculated based upon the empirical Bayes approach and moderated t-statistics implemented in Bioconductor's limma package [ 71].
Instead of the above ordinary T-statistics, regularized T-statistics, implemented in R package st, are also included in our deGPS.
Differential gene expression analysis between patient groups identified by the clustering analysis was performed using empirical Bayes-moderated T-statistics implemented in "limma" [ 18].
Genes differentially expressed between synchronous and metachronous lesions were selected by the permutation-based t-statistics implemented in the SAM algorithm (Tusher et al, 2001).
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