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This endeavor was unsuccessful on a statistically significant basis across all calibration basins, possibly due to potential errors in the soils or geology maps, or in the PRISM climate data, or due to human activities that are affecting basin hydrology at the watershed scale.
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Although we observed these differences consistently and the differences were statistically significant, the biological basis and significance of these observations remain unknown, and additional data are needed to address this question.
All p values were 2-sided and reported as being statistically significant on the basis of a significance level of 0.05.
All p values were two-sided and reported as being statistically significant on the basis of a significance level of 0.05.
aThese analyses are based on n = 3189 patients; missing values were imputed b p values marked in bold are statistically significant on the basis of a significance level of 0.05.
A partial F-test, testing how the coefficient of determination differs when a variable is excluded, given that the variable is not statistically significant, is the basis for excluding variables from the model.
Differences can be observed in all the demographic categories we tested, approximately half of which could be considered statistically significant on the basis of whether their confidence interval overlaps with the confidence interval of the main prediction (these are marked with an asterisk).
Data were also statistically significant on the basis of the Fisher's exact test (Table 1).
The association of one SNP (rs743682) in FGFR3 for European women was found to be statistically significant on this basis.
We also assessed the sensitivity, specificity, the positive predictive value, the negative predictive value and the likelihood ratio of factors that were statistically significant on the basis of the univariate analysis performed to predict complete recall of the clinical trial.
Differentially expressed proteins were defined as statistically significant on the basis of >1.5 fold up and down regulation in HCC patients compared with cell line or more changes in expression intensity (p < 0.05).
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