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Because of the large number of statistical tests conducted in Q-statistics run across complete residential histories, multiple testing bias is a concern.
Due to the number of statistical tests conducted overall, however, some statistically significant differences could be due to chance.
This is not likely to explain all of the significant associations we observed, however: out of the 246 statistical tests conducted, 43% were statistically significant.
Given the large number of statistical tests conducted, we would have expected at least three statistically significant associations; thus, these quartile associations are likely due to chance.
Before the primary analyses, data were examined for violations of assumptions of the statistical tests conducted (that is, multiple regression).
GWAS data must be analyzed with considerations for an inflated rate of false positives among the numerous statistical tests conducted.
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† While 95% Confidence Intervals are not listed due to space limitations, the estimates with appropriate statistical testing conducted on the various differences are reliable according to the Census Bureau.
All statistical tests were conducted in Statistica 8 (Statsoft Inc .. Random resamples were conducted in R [25].
All statistical tests were conducted using IBM SPSS statistics 20 software.
All statistical tests were conducted two-sided and considered statistically significant when p < 0.05.
All statistical tests were conducted with SPSS Statistics 20 (IBM SPSS Statistic, Version 20, IBM Corporation, New York, USA).
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