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Therefore, we developed a novel statistical framework incorporating replicate exome sequencing to identify and prioritise true somatic mutations (Lower et al, 2012).
This emphasizes the necessity of a rigorous statistical framework that incorporates genomic features such as recombination rate when interpreting polymorphism levels.
However, the only method allowing inference of a detailed gene history through species-tree guided gene-tree reconstruction implemented in a reliable statistical framework does not incorporate HGT events, which are prominent features of bacterial evolution (Åkerborg et al. 2009).
(iii) It can be easily made compatible with statistical frameworks.
This analysis necessitates adequate statistical frameworks, such as multilevel modelling.
Hybrid spatial modelling frameworks, incorporating statistical models (in the form of weight-of-evidence approach) along with cellular automata functions, therefore, have been used to comprehend the dynamism of rapid urban growth from 1988 to 2005.
Our statistical framework can be easily expanded to incorporate additional data.
However, the Bayesian statistical framework is general enough to instead incorporate knowledge of the dynamics of physical gene gene interactions.
Thus, an important future direction is also to extend the statistical framework of our dynamic methods to incorporate the characterization of isoform diversity in time course in detecting differential expression.
We used a modified G test to identify QTL regions and developed a model-based statistical framework to resolve individual peaks by incorporating recombination rates.
Because not all information regarding errors can be fully incorporated into the statistical framework, the proper SNP filtering strategies are recommended to reduce the error rates [ 24].
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