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While we avoid the use of matched normal DNA at this step, we do use a high-quality subset for germline event filtering after statistical assessment (Methods).
The approach taken by van der Voet et al. (1), that partitions differences between the GM plant, comparator and reference varieties (i.e. the overall genotype variation) into separate components, differs from previous statistical assessment methods in which the variance component between reference varieties was not estimated (e.g. [ 4- 6]).
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Estimation of DSS for patients was influenced by the statistical assessment method.
Of course, any statistical assessment method developed should also take into account the possibility of having more than one correct peptide per spectrum.
Catch-at-age (or catch-at-length) data are one of the major components of most modern statistical stock assessment methods.
Lastly, statistical standardization within assessment methods provided a common set of z-scores which would be expected to improve inter-laboratory comparability.
Secondarily, goodness of symmetry was confirmed by statistical assessment using two formal methods, Begg rank correlation test and Egger regression asymmetry test (11, 12).
In addition, we extracted the following details for each study article: number of individuals with and without diabetes, type of outcome (definition and data collection and assessment methods), statistical analysis, number of days lost per year, percentage of individuals with the outcome, number of years retired earlier, and summary measure of dependent variable effect with 95% CI or P value.
For any empirical learning method, statistical assessment of the model robustness is an important process.
The disparate findings between the studies may be a result of the differences in the study population, dietary assessment methods, or statistical methods used.
Statistical significance of assessment method outcomes was calculated with an unpaired Student's t test.
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