These abnormalities reached statistical significance for N1 LEPs component, generated in the secondary somatosensory cortex (SII), but not for N2/P2 complex, generated in the insula and anterior cingulated cortex (ACC).
As consequences, they may increase random effects on FA and thus decrease statistical power in detecting abnormalities of the fornix and cingulum regions in schizophrenia.
Statistical analysis of chromosomal abnormalities and total number of breaks between different groups and treatments were performed using the Kruskal-Wallis test.
Both contrasts were assessed (W-PET > W-MRI and W-MRI > W-PET) to generate statistical maps reflecting predominant structural abnormalities or glucose hypometabolism.
We excluded the DMRs harboring UPD or copy number abnormalities for the statistical analyses.
There was a significant statistical association between childhood developmental abnormalities and EOS/VEOS (OR: 37.1, 95% CI: 3.8-1654.1; P < 0.001).
We found a significant statistical association between childhood developmental abnormalities and the risk for schizophrenia, particularly affecting relational skills and learning.
This might be due to differences between patients and the normal populations examined, but might also be due to differences in the statistical methods used to detect abnormalities.
There has been debate regarding whether VBM analyses have sufficient statistical power to detect structural abnormalities in individual brains [Ashburner and Friston, 2000].
Moreover the study shows a statistical association between childhood developmental abnormalities and EOS/VEOS, with particular reference to early relational skills and cognitive ability, in support of the neurodevelopmental model of disease.
The cause of eye abnormalities is unknown, yet the lack of association with human disturbance and the significance of year sampled in our statistical model suggest that eye abnormalities in Alaskan wood frogs are more likely to be associated with something that occurs statewide and changes annually, such as UVB or climate.
