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(a) Statistic comparison under high SNR and (b) statistic comparison under low SNR.
A logistic regression was used to construct the propensity score including variables on clinical relevance or statistic comparison on univariate analysis.
The statistic comparison was made among all the groups (operated knees of treated animals), the positive and the negative controls.
Statistic comparison between groups was done using the Mann–Whitney U test or the Kruskal Wallis test followed by post hoc Dunn's test to compare three or more groups.
Statistic comparison was performed using the Student's t-test, one-way ANOVA analysis, Mann Whitney test, or Kruskal Wallis test, as appropriate, with the significance level at P<0.05.
The biological replicates of ADS collected at different sampling times showed visible variation in taxa composition (R averagely around 0.8, Additional file 1: Table S2, See Additional file 1: Figure S3 for significantly changed taxa between biological replicates), thus the mean value of biological replicates (when available) were used for statistic comparison among sludge microbiomes.
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Statistic comparisons of the ABC genes in SALL4 high- or SALL4 low- group were made using student t-test.
We generated networks to make statistic comparisons.
Statistic comparisons were performed using SPSS 11.0.
Statistic comparisons were done using unpaired two-tailed t-test, except that the Kolmogorov Smirnov test was used for data analyses on AMPAR mEPSCs.
To determine significance of the results, statistic comparisons were performed with a (one sample test or paired test) Student's t-test.
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