IQWiG holds a critical attitude towards the use of models and rejected the use of quality-adjusted life years in its statement of methods published in December 2006 [ 35].
In its statement of "Methods for Assessment of the Relation of Benefits to Costs in the German Statutory Health Care System" published in January 2008, an efficiency frontier approach to economic evaluation was recommended [ 36].
Also its revised statement of general methods published in May 2008 does not address the issue of decision-analytic modelling or QALYs and focuses on the establishment of patient benefit on the basis of clinical trials [ 38].
These approaches are all equivalent in determining the most sensitive method, but the model comparison approach also allows a principled statement of whether a method is significantly more or less sensitive than another method.
The German philosopher Ernst Cassirer demonstrated the likelihood that Galileo was fond of the Meno because it contained the first statement of the "hypothetical" method, a modus operandi that characterized Galileo's own scientific practice and that would come to be known as one of the chief principles of the "new science".
The film is the most ambitious statement of Curtis's methods and his message since his 2004 series The Power of Nightmares, which prophetically examined the ways that western governments exploit fears of terrorism to exert control.
8 34–38 We extracted the major statements of their methods guidance with respect to choosing the appropriate research design in online supplementary table S1.
26 Although, overall, we adhere to the PRISMA-P statement, the method of dealing with publication bias (item 16) is not specified in this protocol.
In the ATS-ERS statement, the method of Bland and Altman is described as the preferred method for investigating the random variation, and this method makes the type of spread visible [ 5, 11].
While the central statement of the Gaussian dispersion method, namely the hypothesis of "normal" distribution of the pollutant concentrations, occurs only in completely ideal situations of atmosphere homogenous turbulence, the softwares based on this mathematical structure are calculation tools of broadest use since they are characterized from an easy mathematical formulation.
Due to the specific statement of the alternative normalization method, the Bcd positional variance in the ensemble became much lower: the standard deviation σ = 1.2%EL.
