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As a caveat to the PM's statement, extraction of coalbed methane (also an "unconventional gas") may begin in Scotland next year, but more likely 2016.
We then assigned each statement to one of seven mutually exclusive domains (see fig 2) based on the International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use E3 19 as well as an assessment of 10 complete response letters included in the study that an investigator not participating in final statement extraction and coding had reviewed.
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Moreover, the PRISMA statement guided the extraction and reporting of data.
According to Heart Rhythm Society latest expert consensus statement on lead extraction [ 4], class I indications include (1) infection, (2) thrombosis or venous stenosis, and (3) directly lead related issues involving functional or nonfunctional leads.
SD – standard deviation; DI – difficulty index; – items with a negative statement were recoded Extraction of the main components eigenvalue > 1); Varimax Rotation with Kaiser Normalization (rotation converged in 7 Iterations).
The Heart Rhythm Society HRSS) consensus statement on lead extraction in relation to venous obstruction states that lead removal is a class I recommendation in patients with ipsilateral venous occlusion preventing additional lead placement when there is a contraindication for using the contralateral side (e.g. contralateral atrioventricular fistula, shunt or vascular access port, and mastectomy).
Following extraction, each statement was coded as to whether the event was negative or positive, and then in relation to four dimensions of patient causality.
The HRS lead extraction consensus statement states that lead removal is reasonable in patients if CIED implantation would require more than four leads on one side or more than five leads through the SVC (Class IIA recommendation).
Data extraction methods statements describe appraisal methods during data abstraction and the methods used to integrate or summarise the data.
"… methodological issues (i.e., sample attrition and exposure to the intervention in the control group) [emphasis added] of a recent randomized, controlled trial rendered its findings inconclusive (MacMillan et al., 2009)…" [ 52], p. 6. Notable in the second extraction is the statement that the control group was exposed to the intervention even though no control women were screened.
Furthermore, the automatic extraction of evidence statements is limited to the availability of full-text articles, as evidence statements mostly occur in full-text versus abstract.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com