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The genomes of both classic and pleomorphic ILC are generally classified as simple (in that they frequently harbour 1q gain and 16q loss and few other alterations) or complex-firestorm (relating to the additional presence of complex, high-level amplifications at the stated loci) [ 18, 23].
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This test is based on a prediction that follows from the neutral theory of molecular evolution, which states that loci exhibiting high rates of divergence between species will also exhibit high levels of variation within species.
The single case where we identified deletions and amplifications affecting the same probes could have been treated as a multi-state locus, but this was not done because we chose to exclude amplifications from this analysis.
In particular, if the probabilities of fusion among gametes are the same for all allelic combinations at the B-locus, random fusion can be stated for this locus.
Lage stated that altered loci with relatively high gene-dosage alterations were detected with high reproducibility.
In these scenarios, p(M d = p(Q d ), although as stated above, marker loci and QTL were in pair-wise linkage equilibrium.
(3) Unless otherwise stated, the term "locus ceruleus" (LC) refers to the locus ceruleus nucleus in the pons, to prevent confusion with the nucleus of an individual LC neuron.
In the Introduction we state that "no loci influencing GR have yet been mapped".
For example, the author claims that 1/3 of the Fugu rubripes genome is functional (this is one of his datapoints), but the original publication only states that "gene loci occupy about one-third of the genome".
This is consistent with classical Hill-Robertson effect theory, which states that a locus that is linked to another locus under selection will experience a reduction in effective population size [ 109].
Ancestral states of loci and snoRNA families were reconstructed using Dollo Parsimony as implemented in DolloP from the Phylip package [ 79].
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