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This combination represents unique, uniform changes in the parent node to M. coreyi and the sister lineage (pos. 324 & 488) plus the state of site 459 (uniquely derived G in the derived M. torreya lineage).
This could then alter the methylation state of site cg24703717 (78bp away) that falls in a YY1 binding peak, a factor whose binding is known to be sensitive to DNA methylation levels (Kim et al., 2003).
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A cellular automaton is a dynamical system on a network whose update rule is local: every site is in one of two (or sometimes more) states, and at every time-step the system is updated according to a rule in which the new state of a site depends only on the states of the sites it is connected to.
Because we sought to use the derived (or "unfolded") site frequency spectrum (SFS), we attempted to determine the ancestral state of each site containing an SNP.
What is interesting, however, is how the numbers point to the changing state of the site, which has transformed itself over the past couple of decades from the internet's auction site to more of a retail storefront.
— Mr. Warren expressed concern about the state of the site.
What is the current state of that site (has it been repurposed or preserved)?
These stats give us a good view into the state of the site for real users, there and then.
As the United States moguls team set off in the afternoon for the first practice runs of the Games, questions loomed over the state of the site.
First analysis of soil conditions, hydrology, geomorphology, and vegetation illustrate the initial state of the site.
In our two monitoring campaigns we aimed to evaluate the influence of microclimate on the conservation state of the site.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com