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MR: You touched on it a little earlier, but can you go a bit more into the state of fusion these days.
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It will be important to characterize the chromatin state of fusion-negative cells to help resolve the question of whether rearrangements in prostate cells have a tendency to occur in regions of open chromatin.
The multiple intermediate states of fusion are classified according to their different FRET efficiency values as characterized previously (13).
Hierarchical clustering based on the selected subset of genes clearly showed that suture tissue samples formed two clusters, mirroring two states of fusion: fused/fusing and unfused (Fig. 2B).
In 5% (of all interactions) or in 14% (of initially-observed fusions) of cases, the initial state of tissue fusion developed into transitory fusion [ 6, 36], and revealed rejection reactions (Table 1).
Steady state operation of fusion reactors avoids many of the cyclic loads and the associated fatigue of pulsed devices.
Long pulse or steady state operation of fusion experiments require data acquisition and processing systems that reduce the volume of data involved.
Data were expressed as fmoles/well[fusion protein], using the relative steady state levels of fusion protein expressed in each strain as the normalization value.
However, these are in fact not separate individuals but transiently separated sub-regions of the entire mitochondrial network that is in some state of fission and fusion at any given time.
To reach our aim, we have evaluated sensitivity and false fusion discovery for eight state-of-the-art fusion finders: Bellerophontes, FusionHunter, FusionMap, FusionFinder, MapSplice, deFuse, ChimeraScan, and TopHat-fusion.
A state of transitory fusion was recorded when partners initially appeared to undergo tissue fusion, but later developed an incompatible reaction.
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