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Someone who as an American, having freedom to do so, searching for a pure state of expression, whether religious philosophy or some kind of philosophy, going from that search to being where he wound up".
Our lives are spent in a constant state of expression these days with texting, tweeting and more.
Yet, the thick paint that adorns his face has trapped him in a state of expression somewhere between fear and mourning.
Now, we must consider import of zinc to activate proteins that maintain a steady state of expression as a potential regulatory step.
Here we have shown that linking a weakened enhancer to a reporter gene allowed the reporter gene to exist in more than one state of expression.
These results lead us to conclude that genes in which expression is driven by a weak enhancer can persist in more than one state of expression for many cell divisions.
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Some evidence suggests that the occurrence of multiple states of expression is in some way related to the action of transcriptional enhancers (reviewed in [5]).
Thus, genes that have been manipulated to lack an enhancer can sometimes exist in at least two states of expression for many weeks.
In all cases, the transition between the silenced and active states of expression is accompanied by histone acetylation and other post-translational histone modifications [1].
Such a result suggests that the active and inactive states of expression are each autocatalytic: that expression above a specific threshold increases the likelihood that the locus will remain active, while expression below that threshold decreases the likelihood of activity.
These functional states of expression are modeled trough discrete variables that take a finite number of values.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com