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Stevens continued her research on the chromosome makeup of various insects, discovering supernumerary chromosomes in certain insects and the paired state of chromosomes in flies and mosquitoes.
Individual chromosomes of the founder generation at the population split (G = 0) were numbered, and the state of chromosomes at each generation was denoted by this number, not by allelic state.
The results demonstrate that the gyramides prevent bacterial growth by a mechanism in which the topological state of chromosomes is altered and halts DNA replication and segregation.
Other outcomes of TE activity, such as their potential to cause DNA double-strand breaks or to modulate the epigenetic state of chromosomes, are less fully characterized.
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This suggests that cohesin turnover may be important to modulate the state of chromosome compaction.
Non-clonal cells represent cells in which unique structural arrangements, telomeric fusions, somatic exchanges and/or different states of chromosome contraction occur.
Finally, the recruitment of structural chromosome proteins, such as condensins and cohesions, able to affect higher order chromatin conformation and the compaction state of the chromosomes (Hirano 2006), as has been found for X-chromosome dosage compensation in C. elegans (Meyer 2010) might confer a fourth mechanism through which Xist coating might cause the heterochromatinization of the Xi.
The resolution of classic chromosomal CGH is limited by the highly condensed state of metaphase chromosomes and further by the optical resolution of the microscopes used to capture the hybridization signals.
There's a bit of road novel as well, when, enlightened as to the actual state of his chromosomes, Cal hitchhikes to -- where else? -- San Francisco.
In particular, this is presumably the case for origins that show delayed replication due to the chromatin state of the chromosomes [27] or to the Cdk1-Clb5 activity [43], [44].
Following this hypothesis, T. blanchardi retained the plesiomorphic diploid state of 50 chromosomes [ 6].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com