Sentence examples for state and alterations from inspiring English sources

Oxidative stress also results in endothelial dysfunction associated with atherosclerosis and subsequent thrombotic complications [ 6], compounded in type-2 diabetes by a sustained hypercoagulable state and alterations in the fibrinolytic pathway.

We anticipate that epigenetic events will become more important within the next few years as researchers develop new methods of analysis to correlate changes in methylation state and alterations in the timing of expression of a functional protein (e.g., phenotype).

Several key features of early sepsis - that is, acute transient increases in body temperature and heart rate, increases in plasma cytokines and stress hormone concentrations, a hypermetabolic state, and alterations of glucose homeostasis - were reproduced.

42 Collectively, a case could be made for exertion and motivation to be affected by the physical state, and thus alterations in stroke play and/or movement patterns.

The changes in the integrin activation state and the alteration in the level of expression of integrins or their ECM ligands have therefore been extensively documented and are thought to contribute to neoplastic progression [ 4- 6].

Inhibition of the mETC will impair oxidative phosphorylation in mitochondria [which may lead to changes in intracellular metabolic state and subsequent alteration in the IKv properties as previously suggested (54)].

Furthermore MMSE summary score and all items did not differentiate patients with minimal HE from those without any signs of HE (i.e. with normal neurological state and without alteration seen in spectral EEG) and did not correlate with MDF values.

Since chemical changes such as those arising from mutations can alter the dynamical states and these alterations, if significant, must be distinctly sensed by the residues in different regions of the protein [32],[33], we next analyzed the differential effects of the mutations on the internal dynamics of the protein [Figure 3].

LCLs from cohort 1 subjects were grown under two environmental conditions (glucose deprived and normal glucose) to measure the effects of stress on exon expression and to examine state and trait-dependent alterations in exon expression in schizophrenia.

Compositional and chemical state alterations, the valence state of the metals, the chemical states of the built-in nitrogen, were monitored by quantitative XPS analysis, performed in situ, without exposing the modified surface to the environment.

We have previously reported disease specific and state dependent alterations in complex I activity, which was shown to play a major role in controlling oxidative phosphorylation in synaptic mitochondria [33], in lymphocytes, and platelets of schizophrenic patients.