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This may imply that the Npm1/Sox2 interaction has a role in pushing ES cells towards ectodermal differentiation, but that once they have started to differentiate into neural stem cells, they can differentiate further without Npm1 involvement.
The cells started to differentiate into adipocytes as early as day 3 and were fully differentiated at day 14 as consistent with increased cell vacuolation of fatty acid observed under the light microscope using Oil O Red staining (Fig. 5a).
However, we found that murine EB proteins were differentially expressed during myogenesis: Both EB1 mRNA and protein levels remained constant during differentiation, whereas EB2 expression was rapidly switched off once cells started to differentiate.
Then we started to differentiate our products.
At this stage the structure, though still just a featureless ball of cells, has started to differentiate into the body's three basic cell types (known as endoderm, mesoderm and ectoderm).
There they started to differentiate.
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Perhaps, once cells start to differentiate, Dap plays a predominant role over Cic to maintain differentiating cells in the G1 phase.
Other sectors are also starting to differentiate their products using provenance information.
(D) Immature OLGs start to differentiate.
Characterization and function of the field, start to differentiate.
The authors showed that Pinus radiata TEs start to differentiate at different times (asynchrony) after transfer of the cells to induction medium.
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