Sentence examples for standing diseases from inspiring English sources
The reference population we used consisted of a sample of Dutch population, comparable to our cohort (n = 4504, UK-tariff): age 50 97 years old (mean = 64, SD = 10), 45% males and 77% low standing diseases like low back pain, asthma and diabetes [13].
This data is consistent with previously published findings on adult populations [9], [15], however it seems that hBD2 expression is less impaired in paediatric compared to adult CD, perhaps suggesting that further regulation occurs in long standing disease.
In the meantime, immunotherapy and long standing disease may complicate the identification of pathogenic DNA methylome changes in IBD.
Post-hoc subgroup analyses of AIM have demonstrated greater remission rates in patients with early disease (<2 years) compared with longer standing disease (>10 years) [ 23].
The patients who were interviewed were at different points on the illness trajectory with many having relatively long standing disease and it is likely that the duration of disease will impact on HRQoL.
Many studies report that the presence of an AL is associated with long standing disease in AS and with a rigid, ankylosed spine [ 22– 24], concluding that an AL is a late complication of AS [ 18].
Patients in the MD phase had slightly lower incidence of RF positivity than patients in the SAD phase, despite long standing disease and 100% anti-cyclic citrullinated peptide (CCP) positivity.
Notably, however, the frequency of post-switch memory B cells was significantly (P = 0.0025) lower in the patient group with shorter disease duration when compared with the long-standing group (median shorter disease: 9.7 ± 2.9% vs longer standing disease: 19.6 ± 2.9%).
cComorbidity: long-standing diseases such as diabetes, hypertension, and musculoskeletal problems.
F. Atzeni et al. evaluated in a real life study the effects of anti-TNF α drugs on RA related disability, suggesting that benefits from these therapies may be relevant also in patients with long-standing diseases.
Secondly, our patients were primarily RA patients with long standing active disease and refractory to conventional therapy.
