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By using recombinant CapG and GFP as internal standards, we calculated that CAPNb2 is expressed at a concentration equivalent to endogenous CapG (Additional file 1: Figure S5B).
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Using direct standardization with the entire diabetes cohort as the population standard, we calculated age-adjusted sex- and ethnicity-specific rates for LEA.
To evaluate the degree of association between our test and the gold standard, we calculated the contingency coefficient, which resulted in 0,65 out of a maximum 0,7(p < 0,001).
By comparison to the internal standard, we calculated the concentration of D933-mer in peripheral plasma at 60 minutes to be 7.0±0.4 nM.
In a similar manner to the polyclonal standard we calculated the amount of antibodies.
For the DIP gold standard, we calculated both precision and recall.
Using this standard, we calculated sensitivity overall and by specific species with 95% confidence intervals (CIs).
8 Using the reference examiner as the gold standard, we calculated the sensitivity and specificity of the participants' ultrasound examinations.
To measure the agreement with the gold standard, we calculated the cumulative number of gold standard associations identified as function of rank.
Third, in the absence of a gold standard, we calculated the sensitivity and specificity of each spirometric criterion, using the alternative cut-off as the reference standard.
Using the ABRF gene set as the gold-standard, we calculated the RMSD for genes with at least two FC in expression.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com