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One possible explanation is that the reference standards in studies classified as at high risk of bias were of sub-optimal sensitivity.
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Although trans-diaphragmatic pressure-time may be considered a gold standard in studies that evaluate new tests of diaphragmatic function, it is highly invasive and uncomfortable for the patient.
HIV/AIDS training for fieldworkers should be standard in studies of this nature, while cognizance should be taken of the dangers of employing local people as fieldworkers in studies of such sensitive nature.
This procedure is standard in studies using the EGI dense-array system and has been validated in a plethora of published studies of EEG and ERPs [30].
Essential revisions: 1) It is standard in studies using siRNAs or shRNAs to rule out off target effects.
Calendar postcards have been used as a gold standard in studies evaluating fall recall at 3, 6 and 12 months in elder cohorts [ 59, 93].
Second, in this study asthma diagnoses as registered by the GP are taken into account, and although often used as a gold standard in studies, this might not be the true reflection of asthmatics in the study population.
The semi-quantitative method proposed by Maki et al. in 1977 [ 5] continues to be the international reference diagnostic method and is used as the gold standard in studies comparing different diagnostic methods.
The 16S rRNA gene has been the molecular standard in studying evolutionary relationships among bacteria (Woese et al. 1990).
This study was the gold-standard in study design, a randomized controlled trial in Belarus between hospitals and clinics that implemented supportive breastfeeding policies and those that did not, therefore eliminating the issues of other environmental factors.
Seven of these interventions used a randomized comparison group design, the gold standard in study design.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com