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First, we established a MI-specific functional biological pathway-process network, with demonstrated sub-networks shown in Figures 2 and 3. We standardized pathway descriptions by their connected GOBP terms, making it easier to compare differences and similarities between pathways, especially those with similar descriptions from different databases.
Contact: [email protected] The Systems Biology Graphical Notation (SBGN, Le Novère et al., 2009) facilitates the representation and exchange of complex biological knowledge in a concise and unambiguous manner: as standardized pathway maps.
In this general context, the present work consisted first in defining a standardized "pathway" representing the operating process, defined as the sequence of all elementary steps between "patient ready for surgery" to "patient operated", and its specific duration.
The model that was created for this study is original in that, on the one hand, it integrates a standardized pathway that is simple, but it also contains all of the elements of variability.
In theory, the patient should follow a standardized pathway [ 26], with guidelines developed jointly by the Ministry of Health, Malaysian Society of Hypertension, and Academy of Medicine of Malaysia [ 27].
As a first step, the clinical pathway was defined as a standardized pathway representing the operating process (defined as the sequence of all of the elementary steps between the "patient ready for surgery" to the "patient operated upon") and its specific duration.
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We also believe that the mEPN scheme has some important advantages over other proposed pathway notation schemes and is therefore a positive contribution to the debate on standardizing pathway depiction.
By standardizing pathway analysis, basing it more globally across functional interactions and controlling for biases, Pathprinting will enable researchers and clinicians to use data from multiple platforms, experiments and animal models to explore complex disease.
Defining clinical pathways from patient activity data could however be very useful for other purposes as well, especially for hospital management where standardizing pathways can greatly improve quality and efficiency.
The cancer reform program is a collaborative effort initiated and incentivized by the central government while multi-professional groups develop the time-bound standardized care pathways, which the regional authorities are responsible for implementing.
Several new nationally standardized registration pathways were introduced in 2008 to further facilitate entry to medical practice [ 9].
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