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Standardized imaging protocols and quantification methods are essential to compare patient populations.
The role of 18F-FDG PET scanning in rupture risk prediction needs to be further investigated, and standardized imaging protocols and quantification methods need to be implemented.
All MRI studies were forwarded to a core laboratory (MedQIA, 924 Westwood Blvd., Suite 650, Los Angeles, CA 90024, USA) for quality control and interpretation to reduce variability in the measurements; the core laboratory also developed standardized imaging protocols for use at the individual study sites, credentialed the sites, and trained MRI technologists at each study site.
All MRI studies were forwarded to an independent core laboratory (MedQIA, Los Angeles, CA, USA) for quality control and interpretation to reduce variability in the measurements; the core laboratory also developed standardized imaging protocols for use at the individual trial sites, credentialed the sites, and trained MRI technologists at each trial site.
The first mixed cohort was obtained from a multi-center study in which standardized imaging protocols were well controlled by selecting the most similar reconstruction kernels between vendors.
Standardized imaging protocols for FDG scans have been published by Shankar et al. [ 9] and Boellaard et al. [ 23] and are available for implementation within multicentre clinical studies.
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Not only would such samples standardize imaging conditions between laboratories and establish milestones for manufacturers, but they would also highlight the effect of post-acquisition thresholding on the final data set.
More work is needed to compare retina brain biological characteristics, describe empirical associations between retina, brain, and prospective biomarkers (including pfHRP2), and to standardize imaging methodology in malaria research.
Miller says the FDA is making progress on the initiative by working with industry on new equipment safety features, working with AAPM and others to establish "reasonable scan protocols and standardize imaging terminology," devising safety checklists for CT operators, and funding efforts to improve training for equipment operators involved in pediatric CT imaging, among other activities.
Given this summary, it can be observed that it is important to decrease the intra-animal variability to a minimum, which can be achieved by standardizing imaging protocols.
Colposcopical evaluations were done using a video colposcopy device (Mediscope, Medison, Korea) with a calibrated rack to standardize imaging distance and illumination.
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