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Standardised Response Means (SRM) were used to evaluate the subscales' responsiveness.
21 (standardised response mean or SRM).mp.mp
One study reported standardised response means for different instruments [ 7].
Standardised response means were higher for SF-6D utilities.
Using the interval transformed data, Standardised Response Means were smaller than when using the raw, ordinal data.
Where possible, pooled effect size, pooled standardised response mean and pooled OR were calculated by meta-analysis, using the inverse of variance method.
With the application of conventional morphological imaging techniques and standardised response criteria based on tumour size measurements, imaging continues to be used to define key study end points.
Response definition was based on changes in tumour size of enhanced lesions on T1-weighted MRI, and following the NCI standardised response criteria (Cheson et al, 1999).
The effect sizes and standardised response means for all four motor tests were either very small, close to zero or had decreased at 4 months and 8 months.
Thus, proper assessment of the response of bone metastases to treatment requires consideration of different aspects of the lesions, use of diagnostic imaging modalities in appropriate combinations, and use of accurate, standardised response criteria.
Validity was tested using factor analysis and Rasch analysis, and responsiveness using standardised response means.
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