For the cognitive assessment, the MRC report recommended using the standardised administration and scoring instructions for the community version of the MMSE[ 10].
Even though none reported non-standardised administration or reading of TST, this can not be ruled out.
This assessment includes administration of standardised assessments by research staff not involved in treatment delivery.
Participants in all studies were assessed with monthly medical history, physical examination, blood testing, treadmill testing, Doppler measurements and administration of standardised questionaries assessing functional status and quality of life.
Competency will confirmed by the administration of a brief, standardised verbal and practical assessment.
The potency of these vaccines was tested prior to the trial in a standardised assay on Balb/c mice, 14 days following administration of the vaccine; peptide specific ELISPOT responses were measured in splenic lymphocytes.
In previous trials [ 1- 3], however, fluid therapy, including administration of HES, was often neither standardised nor limited regarding dose, time frame or selection of patients at risk.
10 The administration of BoNT-A in practice does not reflect the standardised methods adopted in clinical studies because injection schemes are individually determined by the physician.
Local and general solicited adverse events (AEs) were recorded for seven days and unsolicited AEs for 30 d following administration of the polysaccharide challenge by the parent/ guardian on a standardised diary card.
Patients will be contacted by phone for administration of the criterion standard for panic attacks as well as by a standardised interview to collect information for other predictors of panic attacks.
