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Training of HMMs for residential address standardisation was performed by a process of iterative refinement.
Indirect standardisation was performed, assuming the DMARD cohort shared the same risk as the anti- TNF cohort.
Age standardisation was performed by the direct method with reference to 2010 Chinese national population, 19 using four age subgroups 0, 1–4, 5 9 and 10 14 years as the standard population.
Address standardisation was performed on a single-user 1.5 GHz Pentium 4 personal computer with 512 MB of main memory, running the 32-bit Microsoft Windows 2000 operating system.
Age standardisation was performed by direct standardisation, where the Swedish population on 31 December 2009 (4 649 014 men and 4 691 668 women 19) was used as the standard population.
Standardisation was performed with actin measured in the same blots with anti-actin antibody A-20666, Sigma-Aldrich Corp).. Quantifications were shown by the ratios of treated protein expression/untreated protein expression.
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Optimisation and standardisation were performed (see Figure 2 and 3).
Risk-standardisation was performed using hierarchical logistic regression models.
Confidence intervals (CIs) were estimated using the Poisson distribution and age-standardisation was performed using the 2013 European Standard Population 13 for reference.
This standardisation process was performed according to the recommendations of Guillemin (AIMS2-SF) and Bellamy (WOMAC), respectively.
After lavage, FiO2 was increased to 80%, the standardisation manoeuvre was performed as detailed above and the lung volume measurements were repeated while PEEP levels of 0, 3 and 9 cmH2O were maintained in random order.
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