PCAs were performed independently for PET1 and PET2 after z-score standardisation of VT values within genotype groups.
In the future, 'learn on the way' designs based upon biomarker endpoints rather than tumour shrinkage may be employed, although there are important challenges regarding the standardisation of cutoff values and interlaboratory reproducibility, along with the need for prompt assessment must be addressed using such a dynamic approach.
ADC as a quantitative, reproducible predictive tool shows great promise but also needs standardisation of b-values between institutions and further research into identifying threshold values.
A wide range of model designs are used and some standardisation maybe of value in the near future, however it is clear that in vitro models in conjunction with animal studies and human trials offer an excellent way of studying drug dosing to optimise outcomes.
Standardisation: values of selected lines divided by the respective mean value of the inbred control.
Trading firms now promise much more detailed disclosure of trading portfolios and, crucially, standardisation of how they value the often-obscure components of those portfolios.
As we observed this effect despite standardisation of the maneuver itself the value of the current interpretation of static measurements has to be questioned.
Indeed, the ARDSNet investigators have repeatedly shown the value of standardisation of clinical processes for ALI patients in clinical trials, allowing for determination of incremental benefit of new interventions.
Routine inclusion of outcome or performance data could help to demonstrate the community roles and social accountability of medical schools This paper proposes that partial standardisation of these Web documents could enhance their value both internally and for external readers.
But, clinical use of ADC cut-off values for tissue differentiation requires standardisation of acquisition protocol.
However, without standardisation of the methodology, such cutoffs have limited clinical value outwith specific centres.
