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Structures were refined using PHENIX.refine (Afonine et al., 2012) using recommended settings and standard restraint libraries, alternating with manual checking and rebuilding in MAIN (Turk, 2013).
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Restraints on inhibitor bond angles and distances were taken from similar structures in the Cambridge Structural Database [ 55] whereas standard restraints were used on protein bond angles and distances throughout refinement.
Having parsed the nine objections President Obama has so far lodged in the course of five such statements of protest, I believe only two of his objections -- both made in his first protest signing statement -- are arguably outside his standard of restraint.
Compared to direct observation (gold standard), reported restraint use by nursing staff yielded a sensitivity of 87.4% at a specificity of 93.7% (phi = 0.84).
Because I worry that my revelations of anxiety and struggle will be a litany of Too Much Information, a violation of basic standards of restraint and decorum.
We found that PR use in Canadian ICUs is frequent despite provincial legislation and national accreditation standards requiring restraint minimization to maintain patient safety and provide quality health care [ 16, 31].
This trumpet blast would seem to indicate that Mr. Carney has bought into a standard Republican line: restraint is good and spending is bad, even when government dollars are desperately needed by a struggling economy.
Each rat was placed in a standard plastic rat restraint and received 15 Gy of whole head gamma radiation (6000 Curie Cobalt-60 Source, UNMC Experimental Radiation Facility) at a rate of 0.341 Gy/min while unanesthetized.
Analysis of these data yielded the experimental distance restraints and standard deviations for the distance restraints used in subsequent restrained molecular dynamics calculations.
But that doesn't mean we've re-established standards of personal restraint.
With its grotesque villains, elaborate coincidences and passages of political diatribe, Jonathan Coe's What a Carve Up! gloriously offends against many standards of literary restraint.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com