Sentence examples for standard fu from inspiring English sources

At the time the study was designed, irinotecan and oxaliplatin were not available even for experimental use in the adjuvant setting and it was thought that comparing the sequential MTX → FU combination to standard FU LV (maintaining levamisole in both arms) was reasonable and appealing for a large-scale pragmatic trial for three reasons.

Clinical trials conducted throughout the 1990s tested various 5-FU based regimens against the standard 5-FU and levamisole combination.

In the other study, Vanhoefer et al (2000) compared the efficacy and tolerability of FP or etoposide, folinic acid, and 5-FU (ELF) with that of the standard 5-FU, ADR, and sequential high-dose methotrexate (FAMTX).

In concordance with the increased antitumoural efficacy and good tolerance, median survival time was nearly doubled in animals treated with our liposomal formulation, compared with standard 5-FU, thus demonstrating that chemoresistance to 5-FU could indeed be overcome.

These variants exhibit different sensitivities to 5-FU as demonstrated by the finding that a standard 5-FU treatment protocol cured all animals bearing the sensitive C26-10 tumour, while the relatively insensitive C26-B tumour showed only a two-fold increase in doubling time (van Laar et al, 1996a).

The UV-vis absorption spectra of 5-FU at different concentrations in PBS buffer solution and the standard 5-FU concentration curve are shown in Supplementary Figures S10 and S11, respectively.

Interestingly, the found 5-FU concentrations are far less from those that could be achieved by standard 5-FU chemotherapeutic schedules [ 41] which primarily target tumor cells.

In relapsed patients treated with both standard 5-FU and LV, oxaliplatin addition to the combination elicited a 9% greater response to treatment than 5-FU/LV infusion alone (0%) and oxaliplatin alone (1% greater response) with an estimated increase of 2 months in median-survival time [6].

However, survival is still disappointing and not improved over standard cisplatin/5-FU regimens.

IMF-8 showed comparable efficacy with respect to the standard 5-FU in this model with an additional anti-inflammatory activity and by enhancing endogenous antioxidant enzyme levels.

No study could show an improvement of prognosis in multimodal treatment of rectal cancer in comparison to standard 5-FU (de Gramont and Haller, 2008).