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This finding and others suggest that standard dose calculation methods may result in a significant proportion of patients being exposed to suboptimal drug concentration (Gurney, 2005).
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Pencil beam algorithms are still considered as standard photon dose calculation methods in Radiotherapy treatment planning for many clinical applications.
The dosimetrics were calculated by Monte Carlo dose calculation.
For dosimetry of paediatric patients the use of voxel models is a substantial improvement compared to dose calculation based on anthropomorphic paediatric standard phantoms, as the full Monte Carlo simulation takes into account the real anatomy of the patient.
In addition, the limited-angle based acquisition leads to severe structural distortions in DTS images reconstructed by the current clinical gold-standard Feldkamp-Davis-Kress (FDK) reconstruction algorithm, which prohibit accurate target deformation tracking, delineation and dose calculation.
Radiation Dose Calculation.
There is no standard dose.
The endurance improved with the low dose and standard dose (Fig. 2B).
The endurance improved with the low dose and standard dose (Fig. 2F).
The amount of muscle mitochondria was increased with the low dose and standard dose (Fig. 2G).
The muscle mass improved with the standard dose (Fig. 2H).
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