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Lymphocytes in the tumor were also measured by high-power light microscopy and the counts corrected for volume using the standard correction for microscopic depth of field.
We retained clusters with a threshold of p < 0.001 uncorrected at the voxel level, and a corrected threshold of p < 0.05 at the cluster level after SPM standard correction for multiple comparisons.
Thus in this context, standard correction for multiple testing would have resulted as too conservative.
It should however be emphasised that there is a standard correction for restriction of range which cannot also be applied.
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Standard corrections for CT-based attenuation, scatter, decay, and random counts were applied.
Standard corrections for multiple hypothesis testing are usually found to be either very conservative, or having low power.
Within the TK3.1 software, a number of calculations and standard corrections for open-path sensors to produce quality controlled (QC) and quality assured (QA) data were performed after the raw data such as air temperature, water vapour, CO2 and the three components of the wind velocity (u, v and w) had been retrieved from the CR3000 and CR1000 data loggers.
Therefore, the greater homogeneity found for these variables may be explained by this "standard correction" adopted for all the centers.
The external standard method and internal standard correction were applied for quantification of target metabolites.
This problem has long been recognized for epidemiological surveillance, and standard correction factors have been employed for T21 to correct terminations of pregnancy for probability of survival to LB.20, 21 We instead corrected early terminations of pregnancy for probability of survival to 20 weeks GA, essentially calculating prevalence at 20 weeks GA in the absence of intervention.
The simplest method attempted was to first select a subset of markers by using LASSO on the whole data set, and then re-estimate the effects of those markers one-by-one with a simple regression model by the OLS method and perform the standard t-test (including the standard Bonferroni correction for multiple testing).
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