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The treatment strategy eliminated time delays associated with standard coagulation testing and preparation of allogeneic blood products for transfusion: more than half of the patients received haemostatic therapy within an hour of admission to the emergency room (ER).
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Standard coagulation tests, standard thromboelastography (TEG), and heparinase-modified and abciximab-fab-modified TEG were performed immediately before and 30 minutes after commencement of MARS, and after the end of MARS treatment.
In our study the standard coagulation test did not show significant abnormalities.
We performed standard coagulation tests and rotational thrombelastometry before and after each TPE.
Standard coagulation tests were also prolonged (aPTT, INR).
Blood coagulation was monitored using standard coagulation tests, FVIII C, vWF Ag, and thrombelastography.
Correlations for TEG®-variables with standard coagulation tests and hemoglobin are shown in Table 3.
The samples were analyzed for haemoglobin, platelets, standard coagulation tests and colloid osmotic pressure.
ACT, activated clotting time; CSAT, Coagulation Support Algorithm total time; SCT, standard coagulation tests; TMA, time to maximum amplitude.
The secondary aim was to compare the predictive value of ROTEM® parameters with the predictive value of standard coagulation tests.
The effects on basic haemodynamic monitoring, acid base status, electrolyte status, standard coagulation tests and thromboelastometric parameters were investigated.
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