Swing speed (a), stance duration (b), swing duration (c) and print area (d) were significantly altered after 6-OHDA injection.
Swing speed, stance duration, stride length and body speed of all paws correlated with dopamine depletion severity (Table 1).
Stride length, cadence and walking speed were all significantly diminished, while stance duration was significantly prolonged (p < 0.0125).
The following parameters were measured: average speed, body speed for each paw, swing duration, stance duration, stride length, print area and cadence (number of steps per second).
CF stance duration was significantly shorter compared to the other paws, indicating that CF was partly relieved from weight loading and propulsion.
CStr hypermetabolism was strongly associated with several pathological gait changes (decreased swing speed, stride length and body speed) but with only one compensatory effect (increased stance duration).
The two patients evaluated using gait analysis demonstrated slow gait, asymmetric stride length, increased double support and arrhythmic stance duration, and a reduced stance on the operated side (Table 4).
However, it is not clear if this activation is associated with compensation as the greatest correlation between MLR hypermetabolism and gait was found in hindlimb stride length reduction, followed by increased ipsilesional stance duration.
Increased stance duration of all paws correlated with increased contralesional cStr metabolism (R > 0.64, p < 0.0173); increased IH print area however correlated with decreased ipsilateral RFA metabolism (R = −0.69, p = 0.0087).
