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Such a stalling event may provide an opportunity for a cell to switch to a DNA polymerase that is specialized for the bypass of DNA lesions, a process known as translesion DNA synthesis (TLS).
Here, we present ROSE, a deep learning framework to analyze high-throughput ribosome profiling data and estimate the probability of a ribosome stalling event occurring at each genomic location.
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Similarly, in [9], a buffer-level estimation algorithm based on TCP flow is proposed to estimate the QoE of a video user in terms of the expected number and duration of stalling events.
In [10], the problem of YouTube QoE monitoring from an access provider's perspective is investigated, showing that it is possible to detect application-level stalling events by using network-level passive probing only.
In [12, 13], different QoE YouTube models that take into account the key influence factors in the quality perception (such as stalling events caused by network bottlenecks) are presented.
In some human cells, oncogene expression initially causes cells to hyper-proliferate, which leads to aberrantly increased DNA replication rates causing frequent DNA replication fork stalling events.
Indeed, the percentage of fork stalling events, defined as asymmetric DNA replication bubbles at telomeres (see Figure 3A), was dramatically increased by oncogene activation.
To estimate the drag constant of the bead-IFT complex, we analyzed individual stalling events in the optical trap assay and measured the recoil time of the bead after a stall.
The data suggests that the prophage-like elements present in Xylella genomes represent not only an ancient and stalled event that occurred in the genome before the differentiation of the strains, but a dynamic and real-time event by temperate phages dramatically shapes the genome.
The lack of an active control strategy on the power plant resulted in consistent turbine stall events, thus contributing to the excessive loadings imposed to the vanes.
A range of properties has been ascribed to Lis1, including slowing dynein-driven microtubule sliding in multiple motor assays, prolonging dynein stall events under load, and enhancing the microtubule affinity of dynein when ADP and Vi (a phosphate analog) are bound (McKenney et al., 2010; Torisawa et al., 2011; Yamada et al., 2008).
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