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PET is an effective staging study for unknown primaries in HNSCC and has a high sensitivity and specificity in locating extracervical metastases in HNSCC patients.
With CT guidance the study is performed with only oral contrast preparation beginning with a limited number of localising sections planned from the prior staging study.
In the IASLC staging study cohort of 9137 cases, cases reported as 'bronchioloalveolar carcinoma' (BAC) were separated out from other adenocarcinomas and showed a 5YS of only 61%.
Although patients only present with one or two node areas that are clinically affected, the staging study showed dissemination affecting the spleen, liver or bone marrow in 40%, 50% and over 60% of patients, respectively.
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Understanding the test characteristics of these noninvasive staging studies is critical to decision making.
Staging studies were performed as per the Enneking staging system.
Staging studies include chest, abdominal, and pelvic computed tomography.
Retroperitoneal computed tomographic staging studies were interpreted to be normal preoperatively in the entire group.
Open biopsy of the tumor was planned as part of the staging studies.
The use of both whole-body PET and bone scintigraphy as initial staging studies in lung cancer patients provides redundant information about the presence of bony metastases.
Lyman, GH, and Djulbegovic, B. "The challenge of systematic reviews of diagnostic and staging studies in cancer". Cancer Treat Rev 31, no.
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