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This time, the trial followed a staggered design: 25 random schools received the treatment immediately, 25 after two years, and another 25 two years after that.
This staggered design was intended to moderate the effects of the lack of random assignment by providing some evidence that any observed improvements were not a result of maturation.
Moreover, the sensing performances at each mode peak are enhanced by the staggered design, and the highest sensitivity reaches more than 5000 nm per refractive index unit (RIU).
In both species, the fifth staggered design (s7) was excluded from the fit, since the observed linear behavior plateaus near baseline intensity.
Table 1 The table shows the staggered design of probes that cover a 104 bp phyB deletion in the E124 A. thaliana mutant line.
This was a phase I/II, single-center, partially blinded, parallel-group study with a dose-escalating, staggered design (NCT00434512).
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The probes were added to the microarray in nineteen physically staggered designs to cover each region from 2 bp to 49 bp.
These include three SingleCenter designs (center position 18 of each 36-mer changed to all three possible substitute nucleotides), five centered designs (3, 5, 7, 9, and 11 MMs arranged about the center position in a contiguous group), five staggered designs (2, 3, 4, 5 and 7 MMs distributed evenly throughout the 36-mer) and one deletion of the central position.
A variety of trial designs have been proposed to provide information supporting disease modification including change from baseline designs, survival type designs, staggered start designs, and staggered withdrawal designs.
Then, the effects of the training on the emotion-regulation skills of officers were evaluated in a time-staggered design with a waitlist control condition.
This suggests that such extensions of these designs as staggered nested designs [ 18] may have little value in genetic pooling studies.
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