Ovarian follicles at different developmental stages were categorized based on the well-accepted standards established by Pedersen and Peters [21].
The DEGs at the different fruit developmental stages were categorized into functional groups using MapMan [ 23].
Ovarian follicles at different developmental stages were categorized according to standards established by Oktay et al. [ 17].
14 Pathological cancer stages were categorized by using the TNM classification affiliated with the International Union against Cancer.
Based on this analysis, the gene expression levels in the five fruit developmental stages were categorized to rare (TPM < 5), low (TPM > 5 50), moderate (TPM > 50 100), and high (TPM >100) (Additional file 17).
pCR was defined as the absence of invasive cancer within the breast (ypT0/is) and lymph node (ypN0), after extensive sampling, i.e. at least ten sections, 2 4 μm in thickness, from three different regions of the initial tumor site, as proposed by Kuerer et al. 12 Pathological stages were categorized according to the American Joint Committee on Cancer Staging Manual, 7th edition.
Based on the tumor size, descriptions, and number of lymph nodes the stages are categorized in two classes.
In the current staging system utilising T, N, and M factors (AJCC Cancer Staging Manual, 7th Edition, 2010) (Edge et al, 2010), the pancreatic cancer stages are categorized as follows: Stage IA, T1 N0 M0; Stage IB, T2 N0 M0; Stage IIA, T3 N0 M0; Stage IIB, T1 3 N1 M0; Stage III, T4 N-any M0; and Stage IV, T-any N-any M1.
A total of 224 genes out of 302 genes, including 169 genes that exhibited increasing expression trends in the 24h_vs_3d stage and 55 genes that displayed increasing expression trends in the 3d_vs_8d stage, were categorized into 50 pathways (Additional file 5: Table S3), among which 25 pathways had at least two genes (Fig. 5a).
Pathological stage was categorized as organ-confined (T1/T2) or not organ-confined (T3/T4) disease.
The trial stage was categorized as completed, ongoing, terminated, or suspended; sponsor types were industry, central or local government body, hospital, or university; study designs were observational, interventional, randomized, and non-randomized; interventions were biological, behavioral, dietary supplement, device, procedure, drug, gene transfer, other, and not specified.
