Locomotor disorders were associated with an average increase of 12 d to conception, with wide variation depending on lesions and stage of occurrence.
From an operational point of view, since all detected waves matched the same criteria, irrespectively from the sleep stage of occurrence, we refer to all detected waves as sleep slow oscillations (SSOs).
We observed that in the very initial stages of disease occurrence, when there was feeble hyperautofluorescence in the areas of new lesions, the OCT showed hyperreflectivity in the outer retinal layers that was fuzzy and ill defined.
Some of the 'processes' postulated by process philosophers are—in agreement with our common-sense understanding of processes temporal developments that can be analyzed as temporally structured sequences of stages of an occurrence, with each such stage being numerically and qualitatively different from any other.
Higher stage, time of occurrence (synchronous MPM), and order of occurrence (LCF MPM) were significantly associated with poorer OS.
This leads to an impaired immune response, setting the stage for occurrence of opportunistic infections.
Over the years, it has been demonstrated that MDSCs comprise a group of immature myeloid cells belonging both to monocytic and granulocytic lineages, with several stages of differentiation; their occurrence depends on tumor-derived soluble factors, which guide their expansion and determine their block of differentiation.
Aside from this high occurrence, the zebrafish model has another relevant advantage over mice, with respect to the evaluation of fibrosis development according to reproductive stages – the occurrence of ovarian senescence in zebrafish is spontaneous, whereas in mice it has to be induced through an ovariectomy (Gopalakrishnan et al., 2013).
However, there was no obvious correlation between the absence of imbalances and tumor stage, size or age of occurrence.
