Ai Feedback
Exact(6)
Changes to the central nucleus pulposus (NP) are implicated in the early stages of disc degeneration, where decreasing proteoglycan content and an associated reduction in hydrostatic pressure impair the ability of the disc to evenly distribute and transfer compressive loads between the vertebrae [3].
Studies from our laboratory have shown that the proportion of senescent cells increased significantly with increasing stages of disc degeneration (p < 0.0001) [ 19].
Finally, Gruber et al. [ 31] recently utilized microarray analysis and found more than 4,500 differentially expressed genes between early and advanced stages of disc degeneration.
We compared gene expression profiles among three different stages of disc and ray flower development using a gerbera cDNA microarray that includes 9000 probes representing ESTs from different tissues and treatments [ 22].
At advanced stages of disc translocation and blockade, acoustic symptoms disappear to be replaced by chronic pain and significant restriction of jaw opening range, complicated by tilting the mandible towards the affected side upon abduction.
In the early stages of disc degeneration, when the degeneration is mostly confined to the nucleus, restore of nucleus pulposus normal function or slow down of its degenerative process (matrix breakdown) by providing certain well-rationalized nutraceuticals may be an attractive approach.
Similar(54)
Furthermore, as the authors acknowledge, engrailed normally becomes active in the A compartment at late stages of discs development.
It is now indicated in the text and shown in the new Figure 6 figure supplement 2. Furthermore, as the authors acknowledge, engrailed normally becomes active in the A compartment at late stages of discs development.
Results suggested that AF and NP tissue degeneration are not critical to nutrition-related cell viability at early-stage of disc degeneration.
We suggest that SIRT1 may play a key role in the early stage of disc degeneration in human IVD tissues.
A vacuum disc is considered to be at an advanced stage of disc degeneration and a source of low back pain [ 1].
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com