Sentence examples for stages of dependence from inspiring English sources

For example, cortisol can interact with the brain's reward system, which may contribute to alcohol's reinforcing effects, particularly during early stages of dependence.

But they each also mark the end of a stage of dependence our kids had on us.

East Asia, we might say, is at an earlier but still significant stage of dependence (Japan, world's largest LNG importer, now gets 10percentt of its total from Russia), but has been eager for new deals.

They offer protection against seizures in a range of models and seem to inhibit certain stages of drug dependence in preclinical assessments.

This also suggests the presence of obligatory intermediate stages of water dependence to reproduction.

Alterations in HPA axis activity can play different roles at different stages of alcohol dependence.

Considerable research has been devoted to identifying potential underlying mechanisms of the HPA axis dynamics that contribute to progressive stages of alcohol dependence, and the available evidence support several of these potential mechanisms.

Using a familial aggregation design, we tested the hypothesized two-stage model of dependence on illicit substances and alcohol in a large, nationally representative sample.

The American Psychiatric Association (DMS-IV) differentiates between substance abuse, considered an earlier stage of addiction, and substance dependence.

The evidence shown here suggests that one of alcohol's primary effects, in the early stages of development of dependence (represented here by the binge-drinking mouse model), is the transcriptional activation of genes involved in synaptic signaling, endocytic transport, and inflammatory response.

Alterations in HPA axis regulation are associated with problematic alcohol use and dependence; however, the nature of this dysregulation appears to vary with respect to stage of alcohol dependence.