After the interval, Finn, roared on by the crowd, was irresistible, bowling with genuine pace – up to 92mph at one stage – accuracy and consistency.
Four of 5 studies that assessed tumor staging accuracy and 5 of 8 that assessed nodal staging accuracy concluded that EUS was superior to CT.
Body coil MRI has shown T- and N-stage accuracy ranging from 59%to9595% and 39%to95%5%, respectively.
However, when combined to CXCL13 and MMP-9 or IgM, it helped in reaching a significantly increased staging accuracy.
Endorectal coil MRI has shown improved T- and N-stage accuracy, with rates of 66%to9191% and 72%to79%9%, respectively [91, 92].
Recent data have called into question the staging accuracy of EUS, particularly in patients with early disease.
The addition of EUS-FNA may enhance extramesenteric lymph node metastases detection (M1 disease) and overall staging accuracy.
For detection of deep myometrial invasion, the sensitivity and specificity are 83% and 42%, respectively [30], with an overall staging accuracy of between 58-76% [31].
However, inter-reader variability represents a real limitation for prostate mpMRI, and expertise in reporting is crucial to improve cancer detection and staging accuracy.
In single institution studies, MRI performs better than CT in the depiction of parametrial invasion and overall staging accuracy [57, 71, 72, 74].
