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Correlation during the 56-hour blood stage time course between PfGDV1 sense and antisense transcript levels was the highest of any predicted P. falciparum sense-antisense pair (ρ = 0.96), with PfGDV1 antisense transcript levels typically exceeding PfGDV1 sense transcript levels [Fig. 4F].
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In the second stage, time courses were separated into subject-specific blocks.
As shown in Figure S1 [see Additional file 4], the growth stage time-course profile was significantly different from the profile of S deprivation conditions.
We harvested a total of fifteen samples from two independent P. falciparum blood-stage time courses.
The 1388 samples can roughly be divided into three categories, that is, developmental stage (1 237), time course samples (238 771) and others (772 1388).
The transcriptional changes occurring during this initial breaking of dormancy were far more wide-ranging than at any other stage within the time course with T1-T2, T2-T4 and T4-T6 transitions.
Cluster 8 - Twenty four hours post infestation The final cluster of genes contained the late (L) repressed genes with peak repressed expression at 24 hpi and as with cluster 4 (24 hpi up-regulated) represents the end stage of the time course.
Heart rate remained stable at all stages of hypertrophic development (Table 2) and did not differ from the sham groups, and at no stage over the time course of the experiment did the AAB animals show any signs of heart failure (breathlessness or fatigue).
The new resource, called ExpressionData and available at http://www.expressiondata.org, provides reference datasets for human and several model organisms (mouse, Drosophila, Arabidopsis, rice, and yeast), for different technological platforms, and for a variety of biological dimensions (tissue types, developmental stages, or time courses).
Plectin 1 (Plec1), one of the main components of the cytoskeleton, showed an increase in expression of roughly 3- to 4-fold throughout the early stages of the time course (Table 1).
SSSGPs appear to have a division of labor, with "initiators" expressed only immediately after the start of feeding and "maintainers" expressed at later stages in the time course of feeding and plant response.
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