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The Readiness to Change Questionnaire, designed to assess three stages of motivation to change (precontemplation, contemplation and action stages), was completed by all patients, who were then divided into "Action" (i.e. patients in action stage) and "PreAction" (i.e. patients in precontemplation or in contemplation stage) subgroups.
No significant difference in RFS rate was observed among pathologic T stage subgroups.
No significant difference in CSS rate was observed among pathologic T stage subgroups.
The low patient numbers in stage subgroups limited the power of these analyses.
No significant difference in RFS rate was observed between pathological T stage subgroups.
Moreover, the ratio of methylation frequency does not differ between T1c and T2/T3 stage subgroups.
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3. Eligibility criteria: Cancer stage Subgroup analysis for cancer stage (Table 17).
RFS curves were clearly separated by stage subgroup, and were also significantly separated by TNIK expression group in both stage II and III patients.
For patients in T2 stage subgroup, British patients had a significantly worse RFS and OS than Japanese patients (P<0.01, P<0.01, respectively; Figures 3A and B).
In the T-2 stage subgroup, lymph-node status was significantly associated with RFS and OS (HR: 2.4, 2.1; P=0.03, P=0.03, respectively; Table 3).
Also for patients in the T3 stage subgroup, British patients had a significantly worse RFS compared with Japanese patients (P=0.04), but not a worse OS (P=0.12; curves not shown).
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