Just this week, the federal government's H.I.V. Vaccine Trials Network abandoned plans to finance a late-stage study of Aventis's H.I.V. vaccine after early tests showed little effect.
Isis Pharmaceuticals will delay submitting final results from a late-stage study of its cholesterol drug after United States health regulators asked for additional cancer-related data from two preclinical trials.
The company said earlier that it had hoped to submit an application to the Food and Drug Administration by the end of 2001 after a final-stage study of the product, known as Hemopure, showed the blood substitute was as safe as blood from human donors.
The company last month announced that because of a dangerous side effect, it would halt one late-stage study of the drug and remove some patients from a second study that continues.
Data released Wednesday from an early-stage study of Roche's drug, which is known as MPDL3280A, showed significant tumor shrinkage in 21 percent of 140 patients who had a variety of cancers including lung, melanoma and kidney cancer.
This approach could be considered as an auxiliary method during the early-stage study of the water entry, and it could be further applied to some complicated circumstances, like the water entry of spinning spheres.
Shares of Forest Laboratories and Cypress Bioscience rocketed higher in after-hours trading after they delivered positive results on a late-stage study of their depression drug Milnacipran.
A mid-stage study of the Elan-Wyeth amyloid-blocker did not show a statistically significant benefit, although some subsets of patients did better.
Vaccine maker Dendreon said Thursday that data from a late-stage study of its experimental injection Provenge showed improved survival in men with advanced prostate cancer, compared with patients receiving a placebo.
Immunex and American Home Products, which owns 55% of Immunex, recently began a final-stage study of 1,800 patients to answer the key question: Does Enbrel prolong the lives of heart failure subjects?
