Sentence examples for stage serous from inspiring English sources
OBJECTIVE: To identify gene expression patterns that characterize advanced stage serous ovarian cancers by using microarray expression analysis.
Tumor samples and clinical data were obtained from women with advanced stage, serous invasive disease enrolled through the Australian Ovarian Cancer Study (www.aocstudy.org).org
Ovarian cancer specimens were subjected to a similar histopathologic review, and 11 cases of advanced stage, serous ovarian carcinoma were selected for molecular analyses.
Advanced stage serous tumors account for the majority of invasive ovarian cancers and despite a generally good initial response to cytoreductive surgery and platinum-based chemotherapy, most women face a high risk of recurrence and poor long-term survival [1].
The goal of our marker selection was to identify genes whose protein products are consistently found at higher levels in the blood of patients with early stage serous ovarian cancer than in healthy individuals.
In light of these findings, it may be useful to consider genes highly and specifically expressed in early stage serous fallopian tube cancers as potential markers of serous 'ovarian' cancer (whereas previous efforts focused on late stage ovarian tumors).
The purpose of this study was to define gene expression patterns that are associated with the optimal versus suboptimal debulking of advanced-stage serous ovarian cancers.
The objectives of this study were to assess the effectiveness of the panel in detection of early-stage serous and endometrioid ovarian cancers.
Two independent data sets [high-grade, advanced-stage serous (n = 53) and advanced-stage (n = 119) ovarian tumors] validated the survival score performance.
OBJECTIVE: The purpose of this study was to define gene expression patterns that are associated with the optimal versus suboptimal debulking of advanced-stage serous ovarian cancers.
PATIENTS AND METHODS: A gene expression model that predicts response to platinum-based therapy was developed using a training set of 83 advanced-stage serous ovarian cancers and tested on a 36-sample external validation set.
