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At the initial stage, rings of silica were deposited around the central opening, and raised ridges were formed where adjacent rings were appressed (Fig. 6e).
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An older man next to the stage rang a bell after each name.
Mr. Cruz's bass rumbled, and Mr. Svec, stepping to the edge of the stage, rang out his opening riff.
At this stage, ring components are no longer detectable in distinct structures.
Shortly after this stage, ring-shaped actomyosin bundles, which are spaced regularly along the anteroposterior axis of the embryo, undergo coordinated contraction.
Parasite counts of each morphologically identifiable stage (ring, troph, schizont) were determined from each experimental condition at harvest after the 1 h treatment period.
Even a support-group scene featuring real Iraq war veterans, which could have appeared jarringly staged, rings with understated authenticity.
In mid- and late-stage rings, larger vacuoles containing several hemozoin crystals (Figures 4F, G, and 5F) were present, suggesting that progressive vacuolar fusion was occuring.
In early to mid-stage rings, EM showed endocytosis of erythrocyte cytoplasm into small dense vacuoles with diameters of 150 300 nm (Figure 4A, B).
Our results indicate that in early and mid-stage rings, endocytic vesicles function as individual food vacuoles, each able to break down hemoglobin and generate hemozoin crystals (see [29], [57]), and that in late rings there is a switch to a single vacuole, indicating that new molecules able to facilitate vacuolar fusion are functional at this developmental threshold.
For this experiment, different blood stages (rings, trophozoites and schizonts) were pulsed with [14C]-stearic acid.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com