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LmjMIF2 is found in all life cycle stages whereas LmjMIF1 is found exclusively in amastigotes, the intracellular stage responsible for mammalian disease.
An ideal control strategy is the development of effective vaccines, with potential targets in the asexual blood stage responsible for the clinical manifestation of the disease.
The algorithm that quantifies RR also comprises two stages: a preprocessing stage that identifies and filters interference, and a postprocessing stage responsible for detection of valid breathing cycles and calculation of RR.
Notably, the comparison of the oocyst dataset with the extensively covered proteome of T. gondii tachyzoite, the invasive stage responsible for the clinical signs of toxoplasmosis, identified 154 putative oocyst/sporozoite-specific proteins, some of which were validated by Western blot.
Expression profiling of the three clonotypic lineages dominating T. gondii populations in North America and Europe provides a first comprehensive view of the parasite transcriptome, revealing that ~49% of all annotated genes are expressed in parasite tachyzoites (the acutely lytic stage responsible for pathogenesis) and 26% of genes are differentially expressed among strains.
Differentially expressed transcripts also can be evaluated as potential candidates if they meet the following criteria: the chromosomal location to a region containing a QTL, the importance of the tissue of interest in regulating the expression of the specific quantitative trait, and the critical developing stage responsible for the differences in the specific quantitative trait [ 44].
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Results obtained showed that the main stages responsible for waste stabilization were the two first stages: mechanical separation and anaerobic digestion with a diminution of both RI and BMP around 40% and 60%, respectively, whereas the third stage, composting of digested materials, produced lesser biological degradation (20 30%).
P. falciparum gametocytes are the parasite sexual stages responsible for the human-to-mosquito transmission.
There is increasing evidence that receptor-mediated events impact one or more stages responsible for tumor development in experimental animals and humans.
It is apparently conventional wisdom among malariologists that the spread of resistance can be slowed by drugs which target the parasite stages responsible for infecting mosquitoes (sexual stages called gametocytes).
In the goal to globally eliminate malaria, it is increasingly recognized that antiparasite interventions need to target not only the pathogenic asexual forms of the parasite but also the Plasmodium developmental stages responsible for transmission between the human and the Anopheles hosts.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com