Sentence examples for stage precursor from inspiring English sources

Therefore, the characterization of gene expression profiles of early stage precursor lesions of ovarian cancer could provide new insights and identify novel targets for preventive and treatment efforts.

Immature gametocytes - sexual stage precursor cells - likewise disappear from circulation.

However, mutations in KRAS are predicted to precede those of CDKN2A because of a higher prevalence of KRAS mutations in early stage precursor lesions and the observation that most PanIN lesions containing CDKN2A inactivation also harbor a KRAS mutation.

M-CSF induces expression of RANKL receptor (RANK) as well as supports survival and proliferation in early stage precursors of osteoclast lineages in mouse bone marrow cells [ 3].

This suggests that RAP-011 may promote survival of late-stage precursors.

Such chemical compounds may also effectively target tumour-associated macrophage-lineage cells in early-stage precursors for lung adenocarcinomas, through increasing NPC protein expression.

To evaluate late-stage precursors, 2 × 10 cells cells were stained with carboxyfluorescein succinimidyl ester (CFSE Life Technologiess, Grand Island, NY, USA) according to the manufacturer's protocol and were seeded on the upper surface of the transwell plates.

These observations suggest that Nf1 plays a robust role in constraining BG proliferation specifically at an intermediate precursor stage (Stage II), but not during earlier or later stages (Stage I or Stage III).

On Monday, the American Academy of Neurology released preliminary data from the drug's open label testing stage, a precursor to the controlled double-blind scientific trials currently underway.

This suggests that later stage erythroid precursor cells have limited capacity to influence the extracellular environment, implicating a primary role for macrophages in determining the course of terminal differentiation.

By far the most frequently detected mutated gene was TP53, and these mutations have also been detected in early stage and precursor lesions using the same assay [ 53].