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Higher expression levels of miR-21 in TSCC correlated with advanced clinical stage, poor differentiation, and lymph node metastasis [ 16].
This study showed T2 stage, poor differentiation, and vascular infiltration to be significant predictors of nodal positivity [ 33].
Recognised risk factors for LR after SSM and IBR include: tumour size, stage, poor differentiation and lymph node involvement [ 12].
CpG island methylator phenotype-H CRCs were more frequently associated with older age, advanced T, N category and overall stage, poor differentiation and BRAF mutation.
2, 3 Advanced disease stage, poor prognostic factors at presentation 4, and inherent chemoresistance play a part in the dismal outcomes.
In gastric cancer studies, TCN1 was significantly correlated with cancer stage, poor cell differentiation, lymph node metastasis, and a poor prognosis [ 35].
Similar(33)
Immunohistochemical study of 109 OESCC specimens revealed that NGF overexpression, found in 63 out of 109 patients (57.8%), was associated with lymph node metastasis, distant metastasis, higher TNM stage, poorer tumour differentiation, and poorer survival.
He had spent the intervening years as a journeyman actor in an American theatre that was still in its teething stages — poor scripts, poor training, poor conditions.
Late-stage, poor PS and small-cell histology were associated with a higher likelihood of post-primary care referral, diagnosis and treatment within target.
The univariate Cox regression analysis demonstrated that the prothrombin time, AFP, portal vein invasion, advanced cancer stages, poor differentiation, and higher PTP4A3/PRL-3 expression correlated with both cumulative OS and RFS.
Our current study also found that lost expression of miR-339-5p miR-339-5p miR-339-5preast cancer metastasis to lymph nodes, higher clinical stages, poor overall survival, and poor relapse-free survival of breast cancer patients.
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