Sentence examples for stage of bone from inspiring English sources

The synergistic effect of IL-8 and BMP-2 on initiation stage of bone healing and underlying mechanism were thoroughly investigated in vitro and in vivo.

Although the precise mechanisms by which Dkk2 is involved in osteoblast differentiation remains unclear, the results suggest that Dkk2 may act by antagonizing Wnt/β-catenin signaling at a late stage of bone formation since some of the effects of Dkk2 deficiency were partially reversed by expression FRP3, a different Wnt antagonist.

A histomorphological analysis of the bioceramics implants in rat femoral defect models suggested that both in early and late stage of bone repair, merwinite is more effective in promoting osteogenesis in comparison with HA and in late stage, the rate of new bone formation was faster in merwinite-filled-bone-defect than in HA models.

Brown tumours are a form of cystic fibrous osteitis, the end stage of bone remodelling in primary or secondary hyperparathyroidism [28].

Investigation of cultured haematomas gained from the femur of patients undergoing a total hip arthroplasty allowed the monitoring of immune cells present during the early stage of bone healing.

Second, early cell differentiation (identified by cellular alkaline phosphatase release) was found to be enhanced on the horizontally aligned CNW surfaces, whereas mineralization (identified by cellular calcium production), a later stage of bone cell differentiation, was stimulated by the presence of the vertical CNWs on the surfaces.

Here, we demonstrate that synthetic whitlockite (WH: Ca18Mg2 HPO4 2(PO4)12) nanoparticles can recapitulate early-stage of bone regeneration through stimulating osteogenic differentiation, prohibiting osteoclastic activity, and transforming into mechanically enhanced hydroxyapatite (HAP -neo bone tissues by continuous supply of PO43− and Mg2+ under pHAP -neoical conditions.

Thus, assessing growth factor activity, and tissue regeneration around a biomaterial delivery system is extremely important to optimize the stages of bone healing.

This system uses six stages of bone maturation (Fig. 2).

The radiographs show stages of bone fusion during fracture healing (arrows).

Dynamisation of long bone fractures has been shown to accelerate periosteal callus formation and increase mechanical stiffness during early stages of bone healing [50, 51].